Welcome to the Gingras Lab!

We are a signal transduction and proteomics lab located in the Samuel Lunenfeld Research Institute at the Mount Sinai Hospital in Toronto.

Reversible protein phosphorylation is mediated by a network of protein kinases and phosphatases that regulate the response of cells to environmental stimuli. Importantly, misregulation of this process has been implicated in numerous diseases, including cancer, diabetes and Alzheimer's disease. Our laboratory is interested in understanding how serine/threonine phosphatases participate in this regulation. We are applying quantitative proteomics approaches, as well as an array of biochemical and cell biology techniques, to shed light on this important enzyme family.